Choice of ISO for reasonably bright stars

[Bugdozer]

I have generally been using quite a high ISO setting when trying to image objects such as nebulae and galaxies, to try and capture as much faint detail as possible per sub. My understanding is that using a high ISO reduces the overall dynamic range of the image. This isn't such a problem with an extended target where the detail doesn't go to the extremes of black or white and stays more in the middle of the range, but I can imagine for good images of stars, where they are a bright point, a wider dynamic range might be beneficial. 

Therefore, would it be sensible to use a lower ISO when imaging something like an open cluster?