This is what I have and how I use it

GP-DX with SS2K-PC connected by RS232 to a Lindy USB converter 42856, onto a 6-way Belkin USB hub then to a 5m USB extension cable. Autoguided via Shoestring Astronomy's adaptor connected to USB hub.

I use an off-axis guider with a Imaging Source DFK21AS cam connected to a FW extension cable

Canon EOS-350D is connected for pictures/control via USB, and GPUSB for long exposures from Shoestring astronomy. Power comes from a 12V adaptor or internal battery.

Dew control keeps the optics clear.

All above is connected via USB/FW to my Apple PowerBook G4 and I capture using Nebulosity and guide using PHD.